Nakaseke District is a district in Central Uganda. It is named after Nakaseke, the largest town in the district. However, the district headquarters are located at Butalangu. Nakaseke District is bordered by Nakasongola District to the north and northeast, Luweero District to the southeast, Wakiso District to the south, Mityana District to the southwest. Kiboga District and Kyankwanzi District lie to the west and Masindi District lies to the northwest. Butalangu, the location of the district headquarters, lies approximately 66 kilometres, by road, north of Kampala, the capital and the largest city of Uganda. The coordinates of the district are:00 44N, 32 25E.