But the technique, called chromatin immunoprecipitation (ChIP), wasn't working very well, Paro says. "After the crosslink and immunoprecipitation, we realized we would only have very little DNA ...

Lis and Gilmour focused on identifying proteins that bound to specific chromatin sites to understand the mechanisms ... he learned that researchers captured DNA-protein complexes with ...

a technique known as chromatin immunoprecipitation, or ChIP. Next, the investigators queried the identity of the pulled-down DNA by PCR, using primer pairs to amplify short sequences spanning the ...

To study the mechanisms by which transcriptional deregulation causes neoplasia, we are using a chromatin immunoprecipitation protocol to complement three different types of gene expression profiling.