Figure 1: Diagram of the anagen hair follicle, which is in the active growth ... by in vitro correction of a mutation in cultured mutant skin keratinocytes from patients with lamellar ichthyosis ...

While the underlying cause is unknown, HS results in hair follicles that can become blocked and inflamed. Nearby sweat glands and follicles get clogged with oil, sweat, and dead skin cells.

Researchers discovered that employing an air-liquid interface (ALI) culture method significantly enhances hair follicle formation within hiPSC-derived skin organoids compared to traditional ...

For decades, creating human skin models with physiological relevance has been a persistent challenge in dermatological research. Conventional approaches, such as rodent models and two-dimensional skin ...