The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

Its finding: certain structural motifs of proteins in the ER membrane play a central role in this process. The study was carried out as part of the “SCALE – Subcellular Architecture of Life ...

It does that by talking to the membrane fusion protein." More information: Chanwoo Lee et al, Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion, Nature ...

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies. Scientists have ...

It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next-generation ...

In humans, there are two protein families of sodium (Na+)-dependent Pi importers, SLC20 and SLC34. A sole Pi exporter has been identified – SLC53A1. The mitochondrial carrier SLC25A2 transports Pi ...

EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane ...