The short and long of protein tails: How they aid membrane insertion and may impact genetic disorders
The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.
Autism researchers shed light on how α2δ protein mutations affect neurodevelopmental processes
A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to ...
New AI model deciphers the code in proteins that tells them where to go
Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the ...
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AUTISM: INSIGHTS INTO EFFECTS OF MUTATIONS IN NEURONAL PROTEINS
A recent study has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the ...
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Designing proteins with their immediate environment in mind
Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...
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New numbering system facilitates comparability of protein domains
Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies. Scientists have ...
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Study uses clues from body to understand signaling in brain
The first clue about the possible connection between brain and muscle cells came when Janelia scientists noticed something ...
Breakthrough Discovery: Nanoparticles That Neutralize Viruses in the Dark
Scientists have identified nanoparticles that latch onto and destroy virus membranes, opening new possibilities for antiviral ...