We tested valproate, topiramate and lamotrigine in the ... on this well tolerated anticonvulsant to clarify its mechanisms of action using apoptosis and dopamine (DA) content analysis.

Depicted are the hypothesized mechanisms of action of pharmacotherapies used ... the treatment of alcohol use disorder; baclofen and topiramate are not specifically approved for this use.

Topiramate is widely used as an antiepileptic drug in paediatric patients and it has several mechanisms of action. It modulates inhibitory gamma-aminobutyric acid (GABA)-mediated neuroreceptors and ...

3 Department of Neurological Surgery, Emory University, Atlanta, Georgia, USA Idiopathic intracranial hypertension is a disease of unknown aetiology, typically affecting young obese women, producing a ...

Some of the most widely used and effective weight loss medications include: Metformin: Metformin works for weight loss by ...

However, subsequent development of novel targets, using the same strategy failed to replicate this early success and as a consequence central mechanisms of action away from the dural vasculature ...

The purpose of this paper is to review the use of corticosteroids in the management of epilepsy and to briefly outline some of the proposed (but largely unproven), mechanisms of action of these ...

There are five drugs available in the USA with class-1 studies for PAM – propranolol, amitriptyline, topiramate, valproate and gabapentin. These all have efficacy in the class 1 studies ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell ...

There’s such an abundance that we can create a list purely of action shows to look forward to in 2025. Whether you’ve already finished season 2 of Squid Game and are hankering for more action ...

U.S. officials have approved a new type of pain drug designed to eliminate the risks of addiction and overdose associated ...