BMJ1d
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation
1 Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, Amsterdam, The Netherlands Objectives Millions of patients worldwide are treated with therapeutic ...
BMJ1d
Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner
2 Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands 3 Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, ...
BMJ1d
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden Dr A I Catrina, Rheumatology ...
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Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
Correspondence to Professor Gabriela Riemekasten, Department of Rheumatology, University Hospital Schleswig-Holstein—Campus Lübeck, Ratzeburger Allee 160, Lübeck 23538, Germany; ...
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Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE
Correspondence to Dr Jens Y Humrich, Department of Rheumatology and Clinical Immunology, Charité—University Medicine Berlin, Charitéplatz 1, Berlin 10117, Germany; jens.humrich{at}charite.de Here we ...
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“Go upstream, young man”: lessons learned from the p38 saga
Division of Rheumatology, Allergy and Immunology, UC San Diego School of Medicine, La Jolla, California, USA Correspondence to Dr D Hammaker, UCSD School of Medicine, 9500 Gilman Drive, La Jolla, CA ...
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Relationship between serum urate concentration and clinically evident incident gout: an individual participant data analysis
Correspondence to Prof Nicola Dalbeth, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1, New Zealand; n.dalbeth{at}auckland.ac.nz Objectives To ...
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Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial
Objective CONCERTO was a randomised, double-blind, parallel-armed study of methotrexate (MTX) in combination with adalimumab to assess whether an increasing trend of efficacy and decreased safety ...
BMJ3d
Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies
2 Division of Rheumatology, University of British Columbia, Vancouver, Canada 3 Centre for Health Evaluation and Outcomes Sciences, Providence Health, University of British Columbia, Vancouver, Canada ...
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Effectiveness of switching between TNF inhibitors in ankylosing spondylitis: data from the NOR-DMARD register
5 Department of Rheumatology, University Hospital of Northern Norway, Tromsø, Norway 6 Department of Rheumatology, Buskerud Central Hospital, Drammen, Norway Correspondence to Dr E Lie, Department of ...
BMJ3d
Pharmacological induction of interferon type I activity following treatment with rituximab determines clinical response in rheumatoid arthritis
1 Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands 2 Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands 3 Department of Molecular ...