Pittsburgh has become one of the top places in the world for the treatment of appendix cancer – a rare cancer affecting one in a million people. Many of them were told they had only months to live until they came to Pittsburgh.

The owner of Trim in Lawrenceville announced on Tuesday that he will seek the Republican nomination for mayor.

On International Holocaust Remembrance Day, the families of two survivors who resettled in Pittsburgh shared their stories.

Jovan Oviedo and the Pittsburgh Pirates have argued the first salary arbitration case of the year. A right-hander who turns 27 on March 2, Oviedo asked for a raise from $765,000 to $1.15 million while the Pirates argued for $850,

On Tuesday, a large group of supporters packed the City Planning Commission to hear arguments about inclusionary zoning measures.

Pittsburgh Mayor Ed Gainey told the Pennsylvania Press Club Monday that he would not work with ICE but instead work to make his city “more welcoming."

Central Florida running back RJ Harvey celebrates after scoring a touchdown against Oklahoma State during the first half of an NCAA college football game, Saturday, Nov. 11, 2023, in Orlando, Fla. (AP Photo/John Raoux) AP

They all represent an ongoing wave of store closures in the Pittsburgh area in the new year and recent months in what’s expected to be a second big year in a row in which closures outpace new store openings in the shopping center industry throughout the country.

A fire at a home in Pittsburgh’s Carrick neighborhood appeared to rekindle on Tuesday morning.The fire was first reported a little after 1:15 a.m. Tuesday at a home on West Cherryhill Street.Crews were able to knock down that fire.

Former NFL quarterback Dan Orlovsky hopes that the Pittsburgh Steelers' first call this offseason is to the Los Angeles Rams to check on the availability of star quarterback Matthew Stafford. Orlovsky believes no matter what, the team must figure out their issues at quarterback, and Stafford could be the solution to those issues.

Former Seattle Mariners infielder Adam Frazier has signed a one-year deal with the Pittsburgh Pirates, according to Mark Feinsand of MLB.com. He posted the term

Donald Trump again publicly mused about serving further presidential terms Monday, asking Republican House Speaker Mike Johnson whether he was “allowed to”—just a few days after another House Republican introduced legislation to enable just that.