RTK is a class of transmembrane proteins with intrinsic phosphotyrosine kinase activity, including epidermal growth factor receptor (EGFR), vascular endothelial ... Trametinib, a MEK inhibitor, ...

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve ...

The P2X4 receptor is an ATP-gated ion channel that was proposed as a novel drug target for neuropathic pain, neurodegenerative diseases, epilepsy, and cancer. Animal models are indispensable for ...

Joao Fonseca is the youngest Brazilian to win an ATP Tour singles title Teenager Joao Fonseca underlined why he is one of tennis' most promising stars as he beat Francisco Cerundolo to claim his ...

That's why, if you're big into the creative side of things, you should save up to get yourself a 3D printer. Whether you're looking to use it for cosplay by making your own outfits or creating ...

While the action in Melbourne is over, the results are still being felt. On Monday, the ATP Rankings saw a realignment after the Australian Open. Below is a breakdown of what fans must know about ...

Given that the role of PRMT1 in metabolic regulation has been well-documented, we then investigated whether PRMT1 is involved in transforming 6133 cells through metabolic reprogramming. To assess this ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

See schedule and winners of all ATP Tour, ATP 1000 Masters events and Grand Slams in 2025; more than 4,000 tennis matches and 80 tournaments shown live on Sky Sports; Carlos Alcaraz will defend ...

While his main areas of expertise are maker tools -- 3D printers, vinyl cutters, paper printers, and laser cutters -- he also loves to play board games and tabletop RPGs. Expertise 3D printers ...