CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
GEN11d
AAV Delivered NanoCas CRISPR System Edits Muscle in Non-Human Primates
Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.
Medscape8d
Could Gene Therapy for RA Soon Be Ready to ‘Take Off’?
Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...
AZoLifeSciences on MSN23h
CRISPR-Cas9 Off-Target Effects: Challenges and Solutions
The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
labiotech11d
Akribion Therapeutics emerges from stealth with programmable cell depletion RNA technology
Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...
Healthline8d
Curing Cancer: Newer Treatments to Keep an Eye On
CRISPR is an example of gene editing ... virus kills a cancer cell by replicating inside cancer cells and breaking them open. The cancer-related antigens are then exposed to the body’s immune ...
Phys.org18d
Escaping the endosome: BEND lipids improve LNP mRNA delivery and gene editing
Padilla et al, Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering, Nature Communications ...