We tested valproate, topiramate and lamotrigine in the ... on this well tolerated anticonvulsant to clarify its mechanisms of action using apoptosis and dopamine (DA) content analysis.

Topiramate is widely used as an antiepileptic drug in paediatric patients and it has several mechanisms of action. It modulates inhibitory gamma-aminobutyric acid (GABA)-mediated neuroreceptors and ...

3 Department of Neurological Surgery, Emory University, Atlanta, Georgia, USA Idiopathic intracranial hypertension is a disease of unknown aetiology, typically affecting young obese women, producing a ...

There are five drugs available in the USA with class-1 studies for PAM – propranolol, amitriptyline, topiramate, valproate and gabapentin. These all have efficacy in the class 1 studies ...

Int Ophthalmol Clin. 2014;54(1):103-114. Topiramate is typically started at 25 mg daily and can be titrated up to 100 mg twice daily. It is frequently given in addition to acetazolamide in the ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

But sometimes you don’t want that! Sometimes you just want to escape the increasingly insane world out there into an action movie. Netflix has made a few of their own, but the bulk of the best ...

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs ...

To curate this list, he dives into Max’s catalogue every month to surface exciting, white-knuckle action titles — using his taste and a lifetime of cinema study as his guide, instead of ...

All physicians are faced with the challenge of how to help patients with no approved therapies for their diseases. What are ...

PM Modi must admit 'Make in India' failed, says Rahul Gandhi; BJP hits back NEW DELHI: Congress MP Rahul Gandhi Wednesday alleged that Prime Minister Narendra Modi did not mention the 'Make in ...

The mechanism of action underlying ketamine’s rapid antidepressant effects in patients with depression, both suffering from major depressive disorder (MDD) and bipolar disorder (BD), including ...