Brian Setzer of the Stray Cats says he has been dealing with a health issue that has affected his ability to perform on stage.

Brian Setzer announced on social media on Friday, Feb. 14, that after he realized he could not play guitar, he was diagnosed with an autoimmune disease.

Brian Setzer of Stray Cats and big-band fame reveals he is receiving care for an autoimmune disease that has curtailed his ability to make music.

Setzer said the effects of his illness became apparent during the Stray Cats' 2024 summer tour, the group's first road stint in five years

He scored hits in the '80s and '90s but says it now feels like he has gloves on his hands when he picks up an instrument.

Brian Setzer of the Stray Cats has developed an autoimmune disease that prevents him from playing guitar, according to a recent Instagram post from the Massapequa-raised frontman. Setzer, 65, did not cite a name for the disease, but noted that it has affected his ability to perform other tasks with his fingers.

Stray Cats frontman Brian Setzer has revealed via X that he can no longer play guitar after being diagnosed with an autoimmune disease