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Sickle Cell Disease: A 2024 Update - Front Line Genomics
Jul 9, 2024 · Over the last few months, including just in the last week, there have been multiple reports on new treatments for sickle cell disease. In this feature, we highlight the biggest updates in this field and think about what the future might hold.
AI Models For Protein Structure Prediction
Aug 14, 2024 · Understanding how amino acid sequences translate into complex, three-dimensional structures is a problem that has been puzzling scientists for decades 1.Unlocking this mystery is key to uncovering information about how specific structures allow proteins to carry out specialised functions, opening new frontiers in synthetic biology and personalised medicine.
What is multiplex PCR? - Front Line Genomics
Jul 26, 2021 · The polymerase chain reaction (PCR) is a well-established amplification technique that is widely used to rapidly make millions of copies of a specific DNA sample. It was developed by Kary Mullis in the 1980’s and is based on the ability of DNA polymerase to synthesize a new strand of complementary DNA from a template strand.
Report: The Single-cell and Spatial Playbook 2024
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Black geneticists - Front Line Genomics
Oct 1, 2020 · To mark the start of the UK Black History Month, we would like to share with you some of the most influential Black scientists.
Sample Preparation for NGS – A Comprehensive Guide
Aug 21, 2024 · Common challenges in sample preparation. Challenge 1: Many samples are extracted from a limited number of cells – or even a single cell.These don’t provide enough genetic material alone and so need to undergo PCR. However, this amplification step is prone to introducing bias to the sample.
Report: Proteomics 2025
ABOUT US CONTACT ADVERTISE PRIVACY POLICY Front Line Genomics Limited is registered in England and Wales. Company Number 10421716, VAT: GB 297 742 548. Registered Office: Ground Floor, Cromwell House, 15 …
A brief history of Next Generation Sequencing (NGS)
Jul 26, 2021 · Join David Smith (Mayo Clinic), Shawn Baker (SanDiegOmics) and Tiffany Boughtwood (Australian Genomics) as they discuss how the upcoming shifts within the NGS market could affect genomics research in the future and what impact it may have on healthcare around the world: Exploring the Current Sequencing Landscape The history of DNA sequencing
Proteogenomics: Where next?
Jan 8, 2025 · Proteogenomics offers new, in-depth insight into biology and life, going beyond the DNA to encompass the entire central dogma. However, key challenges remain in getting proteogenomics-based approaches in clinical trials.